15-hydroxyprostaglandin dehydrogenase (NADP+) EC#: 1.1.1.197; ChemWhat Code: 1373265

Product Name 15-hydroxyprostaglandin dehydrogenase (NADP+)
Example Structure Example Structure of 15-hydroxyprostaglandin dehydrogenase (NADP+) EC#: 1.1.1.197
Synonyms 9-ketoprostaglandin reductase, carbonyl reductase, NADP-dependent 15-hydroxyprostaglandin dehydrogenase, NADP-linked 15-hydroxyprostglandin dehydrogenase, NADP-specific 15-hydroxyprostaglandin dehydrogenase, prostaglandin 9-ketoreductase, prostaglandin E 9-ketoreductase, type II 15-hydroxyprostaglandin dehydrogenase
EC Number 1.1.1.197
CAS Registry Number 54989-39-8
Comments Acts on prostaglandins E2, F2¦Á and B1, but not on prostaglandin D2 [cf. EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) and EC 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)]. May be identical with EC 1.1.1.189 prostaglandin-E2 9-reductase.
Cofactor
History
Reactions (13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NADP(+) = (13E)- 11-alpha-hydroxy-9,15-dioxoprost-13-enoate + Nadph.

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