16S rRNA (cytidine1402-2′-O)-methyltransferase EC#: 2.1.1.198; ChemWhat Code: 1376425
Product Name | 16S rRNA (cytidine1402-2′-O)-methyltransferase |
Example Structure | |
Synonyms | RsmI, YraL |
EC Number | 2.1.1.198 |
CAS Registry Number | |
Comments | RsmI catalyses the 2′-O-methylation of cytidine1402 and RsmH (EC 2.1.1.199) catalyses the N4-methylation of cytidine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons. |
Cofactor | |
History | |
Reactions | S-adenosyl-L-methionine + cytidine(1402) in 16S rRNA = S-adenosyl-L- homocysteine + 2′-O-methylcytidine(1402) in 16S rRNA. |
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