16S rRNA (cytidine1409-2′-O)-methyltransferase EC#: 2.1.1.227; ChemWhat Code: 1376472
Product Name | 16S rRNA (cytidine1409-2′-O)-methyltransferase |
Example Structure | ![]() |
Synonyms | 2′-O-methyltransferase, TlyA, TlyAII |
EC Number | 2.1.1.227 |
CAS Registry Number | |
Comments | The bifunctional enzyme from Mycobacterium tuberculosis 2′-O-methylates cytidine1409 in helix 44 of 16S rRNA and cytidine1920 in helix 69 of 23S rRNA (cf. EC 2.1.1.226, 23S rRNA (cytidine1920-2′-O)-methyltransferase). |
Cofactor | |
History | |
Reactions | S-adenosyl-L-methionine + cytidine(1409) in 16S rRNA = S-adenosyl-L- homocysteine + 2′-O-methylcytidine(1409) in 16S rRNA. |
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