16S rRNA (cytosine1402-N4)-methyltransferase EC#: 2.1.1.199; ChemWhat Code: 1376427

Product Name 16S rRNA (cytosine1402-N4)-methyltransferase
Example Structure Example Structure of 16S rRNA (cytosine1402-N4)-methyltransferase EC#: 2.1.1.199
Synonyms methyltransferase RsmH, mraW, RsmH
EC Number 2.1.1.199
CAS Registry Number
Comments RsmH catalyses the N4-methylation of cytosine1402 and RsmI (EC 2.1.1.198) catalyses the 2′-O-methylation of cytosine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons.
Cofactor
History
Reactions S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L- homocysteine + N(4)-methylcytosine(1402) in 16S rRNA.

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