1L-myo-inositol 1-phosphate cytidylyltransferase EC#: 2.7.7.74; ChemWhat Code: 1378875

Product Name 1L-myo-inositol 1-phosphate cytidylyltransferase
Example Structure Example Structure of 1L-myo-inositol 1-phosphate cytidylyltransferase EC#: 2.7.7.74
Synonyms CDP-inositol:inositol-1-phosphate transferase, CTP:inositol-1-phosphate cytidylyltransferase, ICPT, IPCT, Tmari_1425
EC Number 2.7.7.74
CAS Registry Number
Comments In many organisms this activity is catalysed by a bifunctional enzyme. The cytidylyltransferase domain of the bifunctional EC 2.7.7.74/EC 2.7.8.34 (CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase) is absolutely specific for CTP and 1L-myo-inositol 1-phosphate. The enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3′-phosphate, a widespread organic solute in microorganisms adapted to hot environments. In many organisms this activity is catalysed by a bifunctional enzyme. The cytidylyltransferase domain of the bifunctional EC 2.7.7.74/EC 2.7.8.34 is absolutely specific for CTP and 1L-myo-inositol 1-phosphate. The enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3′-phosphate, a widespread organic solute in microorganisms adapted to hot environments.
Cofactor
History
Reactions Ctp + 1L-myo-inositol 1-phosphate = diphosphate + CDP-1L-myo-inositol.

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