2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC#: 2.7.7.60; ChemWhat Code: 1378852
| Product Name | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase |
| Example Structure |  |
| Synonyms | 2-C-methyl erythritol 4-phosphate cytidylyltransferase, 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 2-C-methyl-D-erythritol-4-phosphate cytidylyltransferase, 2-C-methylerythritol 4-cytidylyltransferase, 2C-methyl-D-erythritol-4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2-C-methyl-D-erythritol synthetase, 4-diphosphocytidyl-2-C-methylerythritol synthase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, CDP-ME synthetase, CMS, CTP:2-C-methyl-D-erythritol-4-phosphate cytidylyltransferase synthetase, cytidylyltransferase, cytidylyltransferase, 2-C-methylerythritol 4-, diphosphocytidyl-methylerythritol synthetase, HbCMS, HbCMS1, HbCMS2, IspD, IspDF, LipA, MCT, MEP cytidyltransferase, MEP cytidylyltransferase, MtIspD, YgbP |
| EC Number | 2.7.7.60 |
| CAS Registry Number | |
| Comments | The enzyme from?Escherichia coli?requires Mg2+?or Mn2+. ATP or UTP can replace CTP, but both are less effective. GTP and TTP are not substrates. Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis. |
| Cofactor | Mn2+?or?Mg2+ |
| History | |
| Reactions | Ctp + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol. |
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