carboxylating factor for ICDH, CFI, OGC, oxalosuccinate synthetase
EC Number
6.4.1.7
CAS Registry Number
Comments
A biotin-containing enzyme that requires Mg2+?for activity. It was originally thought [1] that this enzyme was a promoting factor for the carboxylation of 2-oxoglutarate by EC?1.1.1.41, isocitrate dehydrogenase (NAD+), but this has since been disproved [2]. The product of the reaction is unstable and is quickly converted into isocitrate by the action of EC?1.1.1.41?[2].
