23S rRNA (adenosine1067-2′-O)-methyltransferase EC#: 2.1.1.230; ChemWhat Code: 1376478
| Product Name | 23S rRNA (adenosine1067-2′-O)-methyltransferase |
| Example Structure |  |
| Synonyms | NHR, NHR protein, nosiheptide resistance methyltransferase, nosiheptide-resistance methyltransferase, thiostrepton resistance methyltransferase, thiostrepton-resistance methylase, thiostrepton-resistance methyltransferase, TSR |
| EC Number | 2.1.1.230 |
| CAS Registry Number | |
| Comments | The methylase that is responsible for autoimmunity in the thiostrepton producer Streptomyces azureus, renders ribosomes completely resistant to thiostrepton [2]. |
| Cofactor | |
| History | |
| Reactions | S-adenosyl-L-methionine + adenosine(1067) in 23S rRNA = S-adenosyl-L- homocysteine + 2′-O-methyladenosine(1067) in 23S rRNA. |
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