23S rRNA (guanine2069-N7)-methyltransferase EC#: 2.1.1.264; ChemWhat Code: 1376527

Product Name 23S rRNA (guanine2069-N7)-methyltransferase
Example Structure Example Structure of 23S rRNA (guanine2069-N7)-methyltransferase EC#: 2.1.1.264
Synonyms 3S rRNA m7G2069 methyltransferase, bifunctional methyltransferase, m2G2069 methyltransferase, ribosomal large subunit methyltransferase, rlmK, RlmKL, SAV1081, Smu472, ycbY
EC Number 2.1.1.264
CAS Registry Number
Comments The enzyme specifically methylates guanine2069 at position N7 in 23S rRNA. In ¦Ã-proteobacteria the enzyme also catalyses EC 2.1.1.173, 23S rRNA (guanine2445-N2)-methyltransferase, while in ¦Â-proteobacteria the activities are carried out by separate proteins [1]. The enzyme from the ¦Ã-proteobacterium Escherichia coli has RNA unwinding activity as well [1].
Cofactor
History
Reactions S-adenosyl-L-methionine + guanine(2069) in 23S rRNA = S-adenosyl-L- homocysteine + N(7)-methylguanine(2069) in 23S rRNA.

Buy Reagent

No reagent supplier? Send quick inquiry to ChemWhat
Want to be listed here as a reagent supplier? (Paid service) Click here to contact ChemWhat

Approved Manufacturers

Want to be listed as an approved manufacturer (Requires approvement)? Please download and fill out this form and send back to approved-manufacturers@chemwhat.com

Contact Us for Other Help

Contact us for other information or services Click here to contact ChemWhat