23S rRNA (guanine2445-N2)-methyltransferase EC#: 2.1.1.173; ChemWhat Code: 1376381

Product Name 23S rRNA (guanine2445-N2)-methyltransferase
Example Structure Example Structure of 23S rRNA (guanine2445-N2)-methyltransferase EC#: 2.1.1.173
Synonyms 23S RNA m(2)G2445 methyltransferase, m2G2445 methyltransferase, ribosomal large subunit methyltransferase, RlmKL, RlmL, Smu472, ycbY
EC Number 2.1.1.173
CAS Registry Number
Comments The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [1]. The enzyme specifically methylates guanine2445 at N2 in 23S rRNA.
Cofactor
History
Reactions S-adenosyl-L-methionine + guanine(2445) in 23S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(2445) in 23S rRNA.

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