m5C-methyltranferase, NOP2, NSUN1/Nol1, p120, proliferation-associated nucleolar antigen, protein p120, RNA:m5C-Mtase
EC Number
2.1.1.310
CAS Registry Number
Comments
The enzyme, found in eukaryotes, is specific for cytosine2870 of the 25S ribosomal RNA. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae [1].
Cofactor
History
Reactions
S-adenosyl-L-methionine + cytosine(2870) in 25S rRNA = S-adenosyl-L- homocysteine + 5-methylcytosine(2870) in 25S rRNA.