3′-demethylstaurosporine O-methyltransferase EC#: 2.1.1.139; ChemWhat Code: 1376333
| Product Name | 3′-demethylstaurosporine O-methyltransferase |
| Example Structure |  |
| Synonyms | 3′-demethoxy-3′-hydroxystaurosporine O-methyltransferase, staurosporine synthase |
| EC Number | 2.1.1.139 |
| CAS Registry Number | |
| Comments | Catalyses the final step in the biosynthesis of staurosporine, an alkaloidal antibiotic that is a potent inhibitor of protein kinases, especially protein kinase C. |
| Cofactor | |
| History | |
| Reactions | S-adenosyl-L-methionine + 3′-demethylstaurosporine = S-adenosyl-L- homocysteine + staurosporine. |
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