3-hydroxy-D-aspartate aldolase EC#: 4.1.3.41; ChemWhat Code: 1382181
| Product Name | 3-hydroxy-D-aspartate aldolase |
| Example Structure |  |
| Synonyms | D-3-hydroxyaspartate aldolase, d-HAA |
| EC Number | 4.1.3.41 |
| CAS Registry Number | |
| Comments | A pyridoxal-phosphate protein. The enzyme, purified from the bacterium?Paracoccus denitrificansy?IFO 13301, is strictly?D-specific as to the ¦Á-position of the substrate, but accepts both the?threo?and?erythro?forms at the ¦Â-position. The?erythro?form is a far better substrate (about 100 fold). The enzyme can also accept?D-allothreonine,?D-threonine,?erythro-3-phenyl-D-serine and?threo-3-phenyl-D-serine. Different from EC?4.1.3.14,?erythro-3-hydroxy-L-aspartate aldolase. Requires a divalent cation, such as Mg2+, Mn2+?or Co2+. |
| Cofactor | pyridoxal 5′-phosphate |
| History | |
| Reactions | (1) Threo-3-hydroxy-D-aspartate = glycine + glyoxylate. (2) D-erythro-3-hydroxyaspartate = glycine + glyoxylate. |
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