3-hydroxybenzoate-CoA/4-hydroxybenzoate-CoA ligase, 3-hydroxybenzoate¡ªcoenzyme A ligase (AMP-forming), 3-hydroxybenzoyl coenzyme A synthetase, 3-hydroxybenzoyl-CoA ligase, 3-hydroxybenzoyl-CoA synthetase, 3HBL, 4-hydroxybenzoate-CoA ligase
EC Number
6.2.1.37
CAS Registry Number
Comments
The enzyme works equally well with 4-hydroxybenzoate but shows low activity towards benzoate, 4-aminobenzoate, 3-aminobenzoate, 3-fluorobenzoate, 4-fluorobenzoate, 3-chlorobenzoate, and 4-chlorobenzoate. There is no activity with 3,4-dihydroxybenzoate, 2,3-dihydroxybenzoate, and 2-hydroxybenzoate as substrates.
Cofactor
History
Reactions
Atp + 3-hydroxybenzoate + CoA = amp + diphosphate + 3-hydroxybenzoyl-CoA.
