3-(methylthio)propionyl-CoA ligase EC#: 6.2.1.44; ChemWhat Code: 1383652

Product Name 3-(methylthio)propionyl-CoA ligase
Example Structure Example Structure of 3-(methylthio)propionyl-CoA ligase EC#: 6.2.1.44
Synonyms 3-methylmercaptopropionyl-CoA ligase, BTH_DmdB2, BTH_I2141, DmdB, methylmercaptopropionate-coenzyme A ligase, MMPA-CoA ligase, PA4198, PA_DmdB1, PU_DmdB1, RL_DmdB1, RL_DmdB2, RPO_DmdB1, RPO_DmdB2, SAR11_0248, SL1157_1815, SL1157_2728, SPO0677, SPO2045
EC Number 6.2.1.44
CAS Registry Number
Comments The enzyme is part of a dimethylsulfoniopropanoate demethylation pathway in the marine bacteria?Ruegeria pomeroyi?and?Pelagibacter ubique. It also occurs in some nonmarine bacteria capable of metabolizing dimethylsulfoniopropionate (e.g.?Burkholderia thailandensis,?Pseudomonas aeruginosa, and Silicibacter lacuscaerulensis). It requires Mg2+?[2].
Cofactor Mg2+
History
Reactions Atp + 3-(methylthio)propanoate + CoA = amp + diphosphate + 3-(methylthio)propanoyl-CoA.

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