3-oxocholest-4-en-26-oate-CoA ligase EC#: 6.2.1.42; ChemWhat Code: 1383650

Product Name 3-oxocholest-4-en-26-oate-CoA ligase
Example Structure Example Structure of 3-oxocholest-4-en-26-oate-CoA ligase EC#: 6.2.1.42
Synonyms fadD19, steroid-CoA ligase
EC Number 6.2.1.42
CAS Registry Number
Comments The enzyme, characterized from actinobacterium?Mycobacterium tuberculosis, catalyses a step in the degradation of cholesterol. It is responsible for the activation of the C8 side chain. 3¦Â-hydroxycholest-5-en-26-oate can also be used as substrate.
Cofactor
History
Reactions Atp + (25S)-3-oxocholest-4-en-26-oate + CoA = amp + diphosphate + (25S)- 3-oxocholest-4-en-26-oyl-CoA.

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