4-hydroxy-2-ketovalerate aldolase, 4-hydroxy-2-ketovalerate aldolase-aldehyde dehydrogenase (acylation), BphI, class II pyruvate aldolase BphI, DmpFG, HOA, HsaF, MhpE, pyruvate aldolase
EC Number
4.1.3.39
CAS Registry Number
37325-52-3
Comments
Requires Mn2+?for maximal activity [1]. The enzyme from the bacterium?Pseudomonas putida?is also stimulated by NADH [1]. In some bacterial species, the enzyme forms a bifunctional complex with EC?1.2.1.10, acetaldehyde dehydrogenase (acetylating). The enzymes from the bacteria?Burkholderia xenovorans?and?Thermus thermophilus?also perform the reaction of EC?4.1.3.43, 4-hydroxy-2-oxohexanoate aldolase [4,5].
