(4S)-4-hydroxy-2-oxoglutarate aldolase EC#: 4.1.3.42; ChemWhat Code: 1382182

Product Name (4S)-4-hydroxy-2-oxoglutarate aldolase
Example Structure Example Structure of (4S)-4-hydroxy-2-oxoglutarate aldolase EC#: 4.1.3.42
Synonyms 2-keto-4-hydroxybutyrate aldolase, 2-keto-4-hydroxyglutarate aldolase, 2-keto-4-hydroxyglutaric aldolase, 2-oxo-4-hydroxyglutarate aldolase, 2-oxo-4-hydroxyglutaric aldolase, 4-hydroxy-2-ketoglutarate aldolase, 4-hydroxy-2-ketoglutaric aldolase, 4-hydroxy-2-oxoglutarate glyoxylate-lyase, eda, HGA, hydroxyketoglutarate aldolase, Hydroxyketoglutaric aldolase, KHG/KDPG aldolase
EC Number 4.1.3.42
CAS Registry Number
Comments The enzyme from the bacterium?Escherichia coli?is specific for the (S) enantiomer. That enzyme is trifunctional, and also catalyses the reactions of EC?4.1.1.3, oxaloacetate decarboxylase and EC?4.1.2.14, 2-dehydro-3-deoxy-phosphogluconate aldolase. cf. EC?4.1.3.16, 4-hydroxy-2-oxoglutarate aldolase.
Cofactor
History
Reactions (4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.

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