5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase EC#: 2.1.1.258; ChemWhat Code: 1376518
Product Name
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase
Example Structure
Synonyms
acsE, methyltetrahydrofo1ate:corrinoid/iron-sulfur protein methyltransferase, methyltetrahydrofolate corrinoid-iron sulfur protein methyltransferase, methyltetrahydrofolate, corrinoid iron¨Csulfur protein methyltransferase, methyltetrahydrofolate- and corrinoid-dependent methyltransferase, methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase, methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase MeTr, MeTr
EC Number
2.1.1.258
CAS Registry Number
Comments
Catalyses the transfer of a methyl group from the N5 group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein. Involved, together with EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin) and EC 2.3.1.169, CO-methylating acetyl-CoA synthase, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea.
Cofactor
History
Reactions
A [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate = a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate.
