6-carboxytetrahydropterin synthase EC#: 4.1.2.50; ChemWhat Code: 1382105

Product Name 6-carboxytetrahydropterin synthase
Example Structure Example Structure of 6-carboxytetrahydropterin synthase EC#: 4.1.2.50
Synonyms 6-carboxy-5,6,7,8-tetrahydropterin synthase, 6-pyruvoyltetrahydropterin synthase, CPH4 synthase, PTPS, QueD
EC Number 4.1.2.50
CAS Registry Number
Comments Binds Zn2+. Isolated from the bacteria?Bacillus subtilis?and?Escherichia coli. The reaction is part of the biosynthesis pathway of queuosine. The enzyme from?Escherichia coli?can also convert 6-pyruvoyl-5,6,7,8-tetrahydropterin and sepiapterin to 6-carboxy-5,6,7,8-tetrahydropterin [1].
Cofactor Zn2+
History
Reactions 7,8-dihydroneopterin 3′-triphosphate + H(2)O = 6-carboxy-5,6,7,8- tetrahydropterin + acetaldehyde + triphosphate.

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