7-chloro-L-tryptophan 6-halogenase EC#: 1.14.19.60; ChemWhat Code: 1375825
| Product Name | 7-chloro-L-tryptophan 6-halogenase |
| Example Structure |  |
| Synonyms | KtzR |
| EC Number | 1.14.19.60 |
| CAS Registry Number | |
| Comments | An FAD-dependent halogenase. The enzyme, characterized from the bacterium Kutzneria sp. 744, works in tandem with EC 1.14.19.9, tryptophan 7-halogenase, (ktzQ) to generate 6,7-dichloro-L-tryptophan, which is incorporated as a pyrroloindoline in the kutznerides family of natural products. It has a 120-fold preference for 7-chloro-L-tryptophan over L-tryptophan as substrate. |
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