7alpha-hydroxysteroid dehydrogenase EC#: 1.1.1.159; ChemWhat Code: 1373216

Product Name 7alpha-hydroxysteroid dehydrogenase
Example Structure Example Structure of 7alpha-hydroxysteroid dehydrogenase EC#: 1.1.1.159
Synonyms 7-alpha-HSDH, 7-HSDH, 7alpha-HSD, 7alpha-HSDH, 7alpha-hydroxy steroid dehydrogenase, 7alpha-hydroxysteroid dehydrogenase, Bile acid-inducible protein, CA 7alpha-HSDH, Ca7alpha-HSDH, dehydrogenase, 7alpha-hydroxy steroid
EC Number 1.1.1.159
CAS Registry Number 39361-64-3
Comments Catalyses the oxidation of the 7¦Á-hydroxy group of bile acids and alcohols both in their free and conjugated forms. The Bacteroides fragilis and Clostridium enzymes can also utilize NADP+.
Cofactor
History
Reactions 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NAD(+) = 3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate + Nadh.

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