The human enzyme produces ATP in nuclei in situations of high energy demand, such as chromatin remodeling. The reaction is dependent on the presence of diphosphate. In its absence the enzyme catalyses the reaction of EC?3.6.1.13, ADP-ribose diphosphatase.?cf. EC?2.7.7.35, ADP ribose phosphorylase.
Cofactor
History
Reactions
Atp + D-ribose 5-phosphate = diphosphate + ADP-D-ribose.