| Synonyms |
ANS, ANS-1, ANS-2, anthocyanidin synthase, anthocyanidin synthase 1, anthocyanidine synthase, anthocyanin synthase, FcANS1, GbANS, IbANS, LDOX, leucoanthocyanidin dioxygenase, leucoanthocyanidin oxygenase, leucocyanidin dioxygenase, leucocyanidin oxygenase, leucocyanidin,2-oxoglutarate:oxygen oxidoreductase, McANS-1, McANS-2, MdANS, RtLDOX |
| Comments |
The enzyme requires Fe(II) and ascorbate. It is involved in the pathway by which many flowering plants make anthocyanin flower pigments (glycosylated anthocyandins). The enzyme hydroxylates the C-3 carbon, followed by a trans diaxial elimination, forming a C-2,C-3 enol. The product loses a second water molecule to form anthocyanidins. When assayed in vitro, non-enzymic epimerization of the product can lead to formation of dihydroflavanols. Thus when the substrate is leucocyanidin, a mixture of (+)-taxifolin and (+)-epitaxifolin are formed. The enzyme can also oxidize the formed (+)-taxifolin to quercetin (cf. EC 1.14.20.6, flavonol synthase) [2,3]. |
