Requires Mg2+. The enzyme from?Tanacetum vulgare?(tansey) can also use (3S)-linalyl diphosphate or more slowly neryl diphosphate in vitro. The reaction proceeds via isomeration of geranyl diphosphate to (3S)-linalyl diphosphate [3]. The oxygen and phosphorus originally linked to C-1 of geranyl diphosphate end up linked to C-2 of (?)-bornyl diphosphate [4].?cf. EC?5.5.1.8?(+)-bornyl diphosphate synthase.