caffeine synthase EC#: 2.1.1.160; ChemWhat Code: 1376362
| Product Name | caffeine synthase |
| Example Structure |  |
| Synonyms | 1-N-methyltransferase activity, 1NMT, 3, 7-dimethylxanthine methyltransferase, 3,7-dimethylxanthine methyltransferase, 7-N-methylxanthine methyltransferase, caffeine synthase, caffeine synthase 1, CCS, CCS1, coffee caffeine synthase 1, CS, CtCS6, DXMT, DXMT1, N-1 methyltransferase, TCS, TCS1, tea caffeine synthase, tea caffeine synthase 1, theobromine 1-N-methyltransferase |
| EC Number | 2.1.1.160 |
| CAS Registry Number | |
| Comments | Paraxanthine is the best substrate for this enzyme but the paraxanthine pathway is considered to be a minor pathway for caffeine biosynthesis [2,3]. |
| Cofactor | |
| History | |
| Reactions | (1) S-adenosyl-L-methionine + 3,7-dimethylxanthine = S-adenosyl-L- homocysteine + 1,3,7-trimethylxanthine. (2) S-adenosyl-L-methionine + 1,7-dimethylxanthine = S-adenosyl-L- homocysteine + 1,3,7-trimethylxanthine. (3) S-adenosyl-L-methionine + 7-methylxanthine = S-adenosyl-L- homocysteine + 3,7-dimethylxanthine. |
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