Chloromuconate cycloisomerase EC#: 5.5.1.7; ChemWhat Code: 1383478

Product Name Chloromuconate cycloisomerase
Example Structure Example Structure of Chloromuconate cycloisomerase EC#: 5.5.1.7
Synonyms 2-chloro-5-oxo-2,5-dihydrofuran-2-acetate lyase (decyclizing), 2-chloromuconate cycloisomerase, 2CMA-cycloisomerase, CMC, CMCI, Isomerase, chloromuconate cyclo-, MLE II, Muconate cycloisomerase II, Rho-2-CMCl, tfdD
EC Number 5.5.1.7
CAS Registry Number 95990-33-3
Comments Requires Mn2+. The product of cycloisomerization of 3-chloro-cis,cis-muconate spontaneously eliminates chloride to produce?cis-4-carboxymethylenebut-2-en-4-olide. Also acts (in the reverse direction) on 2-chloro-cis,cis-muconate. Not identical with EC?5.5.1.1?(muconate cycloisomerase) or EC?5.5.1.11?(dichloromuconate cycloisomerase).
Cofactor Mn2+
History
Reactions (2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis- muconate.

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