cobalt-factor III methyltransferase EC#: 2.1.1.272; ChemWhat Code: 1376540

Product Name cobalt-factor III methyltransferase
Example Structure Example Structure of cobalt-factor III methyltransferase EC#: 2.1.1.272
Synonyms CbiH60, Precorrin-3 methylase
EC Number 2.1.1.272
CAS Registry Number
Comments Isolated from Bacillus megaterium. The enzyme catalyses both methylation at C-17 and ring contraction. Contains a [4Fe-4S] cluster. It can also convert cobalt-precorrin-3 to cobalt-precorrin-4. The reductant may be thioredoxin.
Cofactor
History
Reactions S-adenosyl-L-methionine + cobalt-factor Iii + reduced acceptor = S-adenosyl-L-homocysteine + cobalt-precorrin-4 + acceptor.

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