cysteine desulfurase EC#: 2.8.1.7; ChemWhat Code: 1379060

Product Name cysteine desulfurase
Example Structure Example Structure of cysteine desulfurase EC#: 2.8.1.7
Synonyms c-ISCS, CD0387, CpNifS, CSD, CsdA, CsdB, CysD, cysteine desulfurase, cysteine desulphurase, cysteine:SufU sulfurtransferase, cysteinedesulfurylase, DndA, hAPE, IscS, L-cysteine desulfurase, Lecsl, Nfs, Nfs1, Nfs1p, Nfs2, NIFS, NifS4, Slr0077, Slr0077/SufS, Slr0387, SufS, SufS2
EC Number 2.8.1.7
CAS Registry Number
Comments A pyridoxal-phosphate protein. The sulfur from free?L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors. The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin) [2]. In?Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation [1].
Cofactor pyridoxal 5′-phosphate
History
Reactions L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor.

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