D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase EC#: 2.7.7.70; ChemWhat Code: 1378869

Product Name D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
Example Structure Example Structure of D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase EC#: 2.7.7.70
Synonyms bifunctional D-beta-D-heptose-7-phosphate kinase/D-beta-dheptose-1-phosphate adenylyltransferase, D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase, D-glycero-D-manno-heptose-1beta-phosphate adenylyltransferase
EC Number 2.7.7.70
CAS Registry Number
Comments The bifunctional protein?hldE?includes?D-glycero-¦Â-D-manno-heptose-7-phosphate kinase and?D-glycero-¦Â-D-manno-heptose 1-phosphate adenylyltransferase activity (cf. EC?2.7.1.167). The enzyme is involved in biosynthesis of ADP-L-glycero-¦Â-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core in Gram-negative bacteria.
Cofactor
History
Reactions D-glycero-beta-D-manno-heptose 1-phosphate + Atp = ADP-D-glycero-beta-D- manno-heptose + diphosphate.

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