D-threonine aldolase EC#: 4.1.2.42; ChemWhat Code: 1382092
| Product Name | D-threonine aldolase |
| Example Structure |  |
| Synonyms | ARDTA, AXDTA, CrDTA, D-TA, D-threonine aldolase, DTA, low specificity D-TA, low specificity D-threonine aldolase |
| EC Number | 4.1.2.42 |
| CAS Registry Number | |
| Comments | A pyridoxal-phosphate protein that is activated by divalent metal cations (e.g. Co2+, Ni2+, Mn2+?or Mg2+) [1,2]. The reaction is reversible, which can lead to the interconversion of?D-threonine and?D-allothreonine [1]. Several other?D-¦Â-hydroxy-¦Á-amino acids, such as?D-¦Â-phenylserine,?D-¦Â-hydroxy-¦Á-aminovaleric acid and?D-¦Â-3,4-dihydroxyphenylserine, can also act as substrate [1]. |
| Cofactor | pyridoxal 5′-phosphate |
| History | |
| Reactions | (1) D-threonine = glycine + acetaldehyde. (2) D-allothreonine = glycine + acetaldehyde. |
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