DELTA3-DELTA2-enoyl-CoA isomerase EC#: 5.3.3.8; ChemWhat Code: 1383268
| Product Name | DELTA3-DELTA2-enoyl-CoA isomerase |
| Example Structure |  |
| Synonyms | 2,3-Enoyl-CoA isomerase, 2,3-trans-enoyl-CoA isomerase, 3,2-trans-Enoyl-CoA isomerase, 3,2-trans-enoyl-coenzyme A isomerase, 3-2trans-Enoyl-CoA isomerase, 3-cis-2-trans-Enoyl-CoA isomerase, Acetylene-allene isomerase, AtECI1, AtECI2, AtECI3, D3,D2-enoyl-CoA isomerase, DCI, DELTA3,DELTA2-enoyl CoA isomerase, DELTA3,DELTA2-enoyl-CoA isomerase, DELTA3-cis,DELTA2-trans-Enoyl-CoA isomerase, DELTA3-cis-DELTA2-trans-enoyl-CoA isomerase, Delta3-Delta2-enoyl-CoA isomerase, DELTA3DELTA2-enoyl CoA isomerase, dodecenoyl coenzyme A DELTA isomerase, Dodecenoyl-CoA delta-isomerase, dodecenoyl-CoA DELTA3-cis-DELTA2-trans-isomerase, dodecenoyl-coenzyme A DELTA isomerase, ECI, ECI1, Eci1p, ECI2, Eci3, Hepatocellular carcinoma-associated antigen 88, Isomerase, dodecenoyl coenzyme A Delta-, Long-chain DELTA3,DELTA2-enoyl-CoA isomerase, MECI, MFE1, PECI, Short chain DELTA3,DELTA2-enoyl-CoA isomerase |
| EC Number | 5.3.3.8 |
| CAS Registry Number | 62213-29-0 |
| Comments | The enzyme participates in the ¦Â-oxidation of fatty acids with double bonds at an odd position. Processing of these substrates via the ¦Â-oxidation system results in intermediates with a?cis- or?trans-double bond at position C3, which cannot be processed further by the regular enzymes of the ¦Â-oxidation system. This enzyme isomerizes the bond to a?trans?bond at position C2, which can be processed further. The reaction rate is ten times higher for the (3Z) isomers than for (3E) isomers. The enzyme can also catalyse the isomerization of 3-acetylenic fatty acyl thioesters to 2,3-dienoyl fatty acyl thioesters. |
| Cofactor | |
| History | |
| Reactions | (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA. |
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