erythromycin 3”-O-methyltransferase EC#: 2.1.1.254; ChemWhat Code: 1376512
| Product Name | erythromycin 3”-O-methyltransferase |
| Example Structure |  |
| Synonyms | EryG |
| EC Number | 2.1.1.254 |
| CAS Registry Number | |
| Comments | The enzyme methylates the 3 position of the mycarosyl moiety of erythromycin C, forming the most active form of the antibiotic, erythromycin A. It can also methylate the precursor erythromycin D, forming erythromycin B, which is then converted to erythromycin A by EC 1.14.13.154, erythromycin 12 hydroxylase. |
| Cofactor | |
| History | |
| Reactions | (1) S-adenosyl-L-methionine + erythromycin C = S-adenosyl-L-homocysteine + erythromycin A. (2) S-adenosyl-L-methionine + erythromycin D = S-adenosyl-L-homocysteine + erythromycin B. |
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