GDP-4-dehydro-6-deoxy-D-mannose reductase EC#: 1.1.1.281; ChemWhat Code: 1373378

Product Name GDP-4-dehydro-6-deoxy-D-mannose reductase
Example Structure Example Structure of GDP-4-dehydro-6-deoxy-D-mannose reductase EC#: 1.1.1.281
Synonyms GDP-4-keto-6-deoxy-D-mannose reductase, GDP-4-keto-6-deoxy-D-mannose reductase (ambiguous), GDP-6-deoxy-D-lyxo-4-hexulose reductase, GDP-6-deoxy-D-mannose reductase, RMD
EC Number 1.1.1.281
CAS Registry Number
Comments This enzyme differs from EC 1.1.1.187, GDP-4-dehydro-D-rhamnose reductase, in that the only product formed is GDP-¦Á-D-rhamnose (GDP-6-deoxy-¦Á-D-mannose). D-Rhamnose is a constituent of lipopolysaccharides of Gram-negative plant and human pathogenic bacteria.
Cofactor
History
Reactions GDP-alpha-D-rhamnose + NAD(P)(+) = GDP-4-dehydro-alpha-D-rhamnose + NAD(P)H.

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