glutaconyl-CoA decarboxylase EC#: 7.2.4.5; ChemWhat Code: 1383943
Product Name | glutaconyl-CoA decarboxylase |
Example Structure | |
Synonyms | carboxyltransferase, decarboxylase, glutaconyl coenzyme A, GCD, pent-2-enoyl-CoA carboxy-lyase |
EC Number | 7.2.4.5 |
CAS Registry Number | |
Comments | The enzyme from the bacterium?Acidaminococcus fermentans?is a biotinyl-protein, requires Na+, and acts as a sodium pump. Prior to the Na+-dependent decarboxylation, the carboxylate is transferred to biotin in a Na+-independent manner. The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme. |
Cofactor | biotin |
History | |
Reactions |
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