glutaconyl-CoA decarboxylase EC#: 7.2.4.5; ChemWhat Code: 1383943

Product Name glutaconyl-CoA decarboxylase
Example Structure Example Structure of glutaconyl-CoA decarboxylase EC#: 7.2.4.5
Synonyms carboxyltransferase, decarboxylase, glutaconyl coenzyme A, GCD, pent-2-enoyl-CoA carboxy-lyase
EC Number 7.2.4.5
CAS Registry Number
Comments The enzyme from the bacterium?Acidaminococcus fermentans?is a biotinyl-protein, requires Na+, and acts as a sodium pump. Prior to the Na+-dependent decarboxylation, the carboxylate is transferred to biotin in a Na+-independent manner. The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.
Cofactor biotin
History
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