heme oxygenase (staphylobilin-producing) EC#: 1.14.99.48; ChemWhat Code: 1375931

Product Name heme oxygenase (staphylobilin-producing)
Example Structure Example Structure of heme oxygenase (staphylobilin-producing) EC#: 1.14.99.48
Synonyms haem oxidase, haem oxygenase, heme oxidase, heme oxygenase, heme oxygenase (decyclizing), heme oxygenase (staphylobilin-producing) 1, heme oxygenase (staphylobilin-producing) 2, isdG, isdI
EC Number 1.14.99.48
CAS Registry Number
Comments This enzyme, which is found in some pathogenic bacteria, is involved in an iron acquisition system that catabolizes the host’s hemoglobin. The two enzymes from the bacterium Staphylococcus aureus, encoded by the isdG and isdI genes, produce 67.5 % and 56.2 % ¦Ä-staphylobilin, respectively.
Cofactor
History
Reactions (1) Protoheme + 5 reduced acceptor + 4 O(2) = 5-oxo-delta-bilirubin + Fe(2+) + formaldehyde + 5 acceptor + 4 H(2)O. (2) Protoheme + 5 reduced acceptor + 4 O(2) = 15-oxo-beta-bilirubin + Fe(2+) + formaldehyde + 5 acceptor + 4 H(2)O.

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