hercynylcysteine S-oxide synthase EC#: 1.14.99.51; ChemWhat Code: 1375936

Product Name hercynylcysteine S-oxide synthase
Example Structure Example Structure of hercynylcysteine S-oxide synthase EC#: 1.14.99.51
Synonyms Egt-1, Egt1, egt1+, ergothioneine biosynthesis protein 1, mug158+/SPBC1604.01, protein SPBC1604.01, SPBC1604.01
EC Number 1.14.99.51
CAS Registry Number
Comments Requires Fe2+ for activity. The enzyme, found in fungal species, is part of a fusion protein that also has the the activity of EC 2.1.1.44, L-histidine N¦Á-methyltransferase. It is part of the biosynthesis pathway of ergothioneine. The enzyme can also use L-selenocysteine to produce hercynylselenocysteine, which can be converted to selenoneine.
Cofactor Fe2+
History
Reactions Hercynine + L-cysteine + O(2) = S-hercyn-2-yl-L-cysteine S-oxide + H(2)O.

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