[histone H3]-lysine27 N-trimethyltransferase EC#: 2.1.1.356; ChemWhat Code: 1376642

Product Name [histone H3]-lysine27 N-trimethyltransferase
Example Structure Example Structure of [histone H3]-lysine27 N-trimethyltransferase EC#: 2.1.1.356
Synonyms CLF, EZH1, EZH2, histone H3 lysine 27 methyltransferase, histone lysine methyltransferase, HMTase, interleukin-5 response element II binding protein, KMT6A, KMT6B, Polycomb repressive complex 2, PRC2, RE-IIBP, SET domain histone lysine methyltransferase, vSET, WHSC1/MMSET isoform RE-IIBP
EC Number 2.1.1.356
CAS Registry Number
Comments This entry describes enzymes that successively methylate the L-lysine27 residue of histone H3 (H3K27), ultimately generating a trimethylated form. These modifications influence the binding of chromatin-associated proteins. The methylation of lysine27 leads to transcriptional repression of the affected target genes. The enzyme associates with other proteins to form a complex that is essential for activity. The enzyme can also methylate some non-histone proteins. Formerly EC 2.1.1.43.
Cofactor
History
Reactions

Buy Reagent

No reagent supplier? Send quick inquiry to ChemWhat
Want to be listed here as a reagent supplier? (Paid service) Click here to contact ChemWhat

Approved Manufacturers

Want to be listed as an approved manufacturer (Requires approvement)? Please download and fill out this form and send back to approved-manufacturers@chemwhat.com

Contact Us for Other Help

Contact us for other information or services Click here to contact ChemWhat