L-cysteinyl-L-histidinylsulfoxide synthase EC#: 1.14.99.52; ChemWhat Code: 1375937

Product Name L-cysteinyl-L-histidinylsulfoxide synthase
Example Structure Example Structure of L-cysteinyl-L-histidinylsulfoxide synthase EC#: 1.14.99.52
Synonyms 5-histidylcysteine sulfoxide synthase, OvoA, OvoA-like protein, OvoAe, OvoAErwin, OvoAt, OvoA_1, OvoA_2, PlOvoA, short OvoA homologue, SpOvoA, sulfoxide synthase
EC Number 1.14.99.52
CAS Registry Number
Comments Requires Fe2+ for activity. The enzyme participates in ovothiol biosynthesis. It also has some activity as EC 1.13.11.20, cysteine dioxygenase, and can perform the reaction of EC 1.14.99.50, ¦Ã-glutamyl hercynylcysteine sulfoxide synthase, albeit with low activity [4].
Cofactor Fe2+
History
Reactions L-histidine + L-cysteine + O(2) = S-(L-histidin-5-yl)-L-cysteine S-oxide + H(2)O.

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