L-rhamnose isomerase EC#: 5.3.1.14; ChemWhat Code: 1383207

Product Name L-rhamnose isomerase
Example Structure Example Structure of L-rhamnose isomerase EC#: 5.3.1.14
Synonyms COB47_0655, Isomerase, L-rhamnose, L-rhamnose isomerase, L-rhamnose ketol-isomerase, L-RhI, L-RI, RhaA, RhaI, Rhamnose isomerase
EC Number 5.3.1.14
CAS Registry Number 9023-84-1
Comments Contains two divalent metal ions located at different metal-binding sites within the active site. The enzyme binds the closed ring form of the substrate and catalyses ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites. Isomerization proceeds via a hydride-shift mechanism. While the enzyme from the bacterium?Escherichia coli?is specific for?L-rhamnose, the enzyme from the bacterium?Pseudomonas stutzeri?has broad substrate specificity and catalyses the interconversion of?L-mannose and?L-fructose,?L-lyxose and?L-xylulose,?D-ribose and?D-ribulose, and?D-allose and?D-psicose [2].
Cofactor divalent cation
History
Reactions L-rhamnopyranose = L-rhamnulose.

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