leucoanthocyanidin reductase EC#: 1.17.1.3; ChemWhat Code: 1375983

Product Name leucoanthocyanidin reductase
Example Structure Example Structure of leucoanthocyanidin reductase EC#: 1.17.1.3
Synonyms ANR, anthocyanidin reductase, BAN, CsLAR, FeLAR1, FeLAR2, FeLAR3, LAR, LAR1, lar2, LARa, LarB, LarC, leucoanthocyanidin 4-reductase, leucoanthocyanidin reductase, leucocyanidin reductase, MdLAR1, MdLAR2, More, MtLAR, PaLAR3, PtrLAR1, PtrLAR3, reductase, leucoanthocyanidin, TcLAR, Vv lar1, Vv lar2
EC Number 1.17.1.3
CAS Registry Number
Comments The enzyme catalyses the synthesis of catechin, catechin-4¦Â-ol (leucocyanidin) and the related flavan-3-ols afzelechin and gallocatechin, which are initiating monomers in the synthesis of plant polymeric proanthocyanidins or condensed tannins. While 2,3-trans-3,4-cis-leucocyanidin is the preferred flavan-3,4-diol substrate, 2,3-trans-3,4-cis-leucodelphinidin and 2,3-trans-3, 4-cis-leucopelargonidin can also act as substrates, but more slowly. NADH can replace NADPH but is oxidized more slowly.
Cofactor
History
Reactions (2R,3S)-catechin + NADP(+) + H(2)O = 2,3-trans-3,4-cis-leucocyanidin + Nadph.

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