lipid A phosphoethanolamine transferase EC#: 2.7.8.43; ChemWhat Code: 1378977
| Product Name | lipid A phosphoethanolamine transferase |
| Example Structure |  |
| Synonyms | Cj0256, EptA, EptAPa, EptC, ethanolamine phosphotransferase, HD_0852, Hp0022, lipid A PEA transferase, lipid A pEtN transferase, lipid A phosphoethanolamine transferase, lipooligosaccharide phosphoethanolamine transferase A, LOS PEA transferase A, LPS phosphoethenolamine transferase for lipid A, lpt-O, LptA, LptH, NmLptA, opgE, PEA transferase, PEA transferase A, pEtN transferase, PEtN-transferase, phosphoethanolamine transferase, phosphoethanolamine transferase A, PmrA, PmrC, polymyxin resistance protein A, polymyxin resistance protein C, sNMLptA |
| EC Number | 2.7.8.43 |
| CAS Registry Number | |
| Comments | The enzyme adds one or two ethanolamine phosphate groups to lipid A giving a diphosphate, sometimes in combination with EC?2.4.2.43?(lipid IVA?4-amino-4-deoxy-L-arabinosyltransferase) giving products with 4-amino-4-deoxy-¦Â-L-arabinose groups at the phosphates of lipid A instead of diphosphoethanolamine groups. It will also act on lipid IVA?and Kdo2-lipid A. |
| Cofactor | |
| History | |
| Reactions | (1) Diacylphosphatidylethanolamine + lipid A = diacylglycerol + lipid a 1-(2-aminoethyl diphosphate). (2) Diacylphosphatidylethanolamine + lipid A = diacylglycerol + lipid a 4′-(2-aminoethyl diphosphate). (3) Diacylphosphatidylethanolamine + lipid A 1-(2-aminoethyl diphosphate) = diacylglycerol + lipid A 1,4′-bis(2-aminoethyl diphosphate). |
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