Acyl protein synthetase, Acyl-protein synthetase, long-chain-fatty-acid-luciferin-component ligase, synthetase, acyl protein
EC Number
6.2.1.19
CAS Registry Number
82657-98-5
Comments
Together with a hydrolase component (EC?3.1.2.2/3.1.2.14) and a reductase component (EC?1.2.1.50), this enzyme forms a multienzyme fatty acid reductase complex that produces the long-chain aldehyde substrate of the bacterial luciferase enzyme (EC?1.14.14.3). The enzyme activates free long-chain fatty acids, generated by the action of the transferase component, forming a fatty acyl-AMP intermediate, followed by the transfer of the acyl group to an internal?L-cysteine residue. It then transfers the acyl group to EC?1.2.1.50, long-chain acyl-protein thioester reductase.
Cofactor
History
Reactions
Atp + a long-chain fatty acid + [protein]-L-cysteine = amp + diphosphate + a [protein]-S-(long-chain-acyl)-L-cysteine.
