lysine 2,3-aminomutase EC#: 5.4.3.2; ChemWhat Code: 1383341
| Product Name | lysine 2,3-aminomutase |
| Example Structure |  |
| Synonyms | AblA, Aminomutase, lysine 2,3-, HD73_2540, KAM, kamA, L-Lysine-2,3-aminomutase, LAM, lysine 2,3-aminomutase, lysine-2,3-aminomutase, Mutase, lysine 2,3-amino-, YjeK |
| EC Number | 5.4.3.2 |
| CAS Registry Number | 9075-20-1 |
| Comments | This enzyme is a member of the ‘AdoMet radical’ (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster and binds an exchangeable?S-adenosyl-L-methionine molecule. Activity?in vitro?requires a strong reductant such as dithionite and strictly anaerobic conditions. A 5′-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of?S-adenosyl-L-methionine, mediated by the iron-sulfur cluster.?S-adenosyl-L-methionine is regenerated at the end of the reaction. |
| Cofactor | iron-sulfur |
| History | |
| Reactions | L-lysine = (3S)-3,6-diaminohexanoate. |
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