lysine 5,6-aminomutase EC#: 5.4.3.3; ChemWhat Code: 1383343

Product Name lysine 5,6-aminomutase
Example Structure Example Structure of lysine 5,6-aminomutase EC#: 5.4.3.3
Synonyms (R)-lysine mutase, 5,6-LAM, beta-Lysine mutase, KamDE, LAM, lysine 5,6-aminomutase
EC Number 5.4.3.3
CAS Registry Number 9075-69-8
Comments This enzyme is a member of the ‘AdoMet radical’ (radical SAM) family. It requires pyridoxal 5′-phosphate and adenosylcobalamin for activity. A 5′-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.
Cofactor cob(II)alamin pyridoxal 5′-phosphate
History
Reactions (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = 2,5-diaminohexanoate.

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