malate dehydrogenase [NAD(P)+] EC#: 1.1.1.299; ChemWhat Code: 1373404

Product Name malate dehydrogenase [NAD(P)+]
Example Structure Example Structure of malate dehydrogenase [NAD(P)+] EC#: 1.1.1.299
Synonyms MDH II
EC Number 1.1.1.299
CAS Registry Number
Comments This enzyme, which was characterized from the methanogenic archaeon Methanobacterium thermoautotrophicum, catalyses only the reduction of oxaloacetate, and can use NAD+ and NADP+ with similar specific activity [1]. Different from EC 1.1.1.37 (malate dehydrogenase (NAD+)), EC 1.1.1.82 (malate dehydrogenase (NADP+)) and EC 1.1.5.4 (malate dehydrogenase (quinone)).
Cofactor
History
Reactions (S)-malate + NAD(P)(+) = oxaloacetate + NAD(P)H.

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