[methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase
Example Structure
Synonyms
corrinoid:coenzyme M methyltransferase, methylated MtmC protein:CoM methyltransferase, methylated [methylamine-specific corrinoid protein]:coenzymeM methyltransferase, methylcobamide:coenzyme M methyltransferase, methylcobamide:CoM methyltransferase, methylcorrinoid:Coenzyme M methyltransferase, methylcorrinoid:CoM methyltransferase, methyltransferase 2, methyltransferase II, MMA-specific methyltransferase, MMA:CoM methyl transferase, MM_1070, MT2, MT2-A, MT2-M, mtaA, mtbA, TMA-specific methyltransferase, TMA:CoM methyl transferase, TMA:CoM methyltransferase, trimethylamine:coenzyme M methyltransferase
EC Number
2.1.1.247
CAS Registry Number
Comments
Contains zinc [2]. The enzyme, which is involved in methanogenesis from mono-, di-, and trimethylamine, catalyses the transfer of a methyl group bound to the cobalt cofactor of several corrinoid proteins (mono-, di-, and trimethylamine-specific corrinoid proteins, cf. EC 2.1.1.248, methylamine¡ªcorrinoid protein Co-methyltransferase, EC 2.1.1.249, dimethylamine¡ªcorrinoid protein Co-methyltransferase, and EC 2.1.1.250, trimethylamine¡ªcorrinoid protein Co-methyltransferase) to coenzyme M, forming the substrate for EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase, the enzyme that catalyses the final step in methanogenesis.
Cofactor
Zn2+
History
Reactions
A [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme m = methyl-CoM + a [Co(I) methylamine-specific corrinoid protein].
![Example Structure of [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase EC#: 2.1.1.247](/wp-content/uploads/enzyme-structure/2.1.1.247.jpg)