methylamine-corrinoid protein Co-methyltransferase EC#: 2.1.1.248; ChemWhat Code: 1376505
| Product Name | methylamine-corrinoid protein Co-methyltransferase |
| Example Structure |  |
| Synonyms | corrinoid-dependent methylamine methyltransferase, MMA methyltransferase, MMA:CoM methyltransferase, MMA:MMCP methyltransferase, MMAMT, monomethylamine methyltransferase, monomethylamine:coenzyme M methyl transferase, monomethylamine:MMCP methyltransferase, MtmB, mtmB1, mtmB2 |
| EC Number | 2.1.1.248 |
| CAS Registry Number | |
| Comments | The enzyme, which catalyses the transfer of a methyl group from methylamine to a methylamine-specific corrinoid protein (MtmC), is involved in methanogenesis from methylamine. The enzyme contains the unusual amino acid pyrrolysine [3]. Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state. During methylation the cobalt is oxidized to the Co(III) state. The methylated corrinoid protein is substrate for EC 2.1.1.247, methylated methylamine-specific corrinoid protein:coenzyme M methyltransferase. |
| Cofactor | |
| History | |
| Reactions | Methylamine + a [Co(I) methylamine-specific corrinoid protein] = a [methyl-Co(III) methylamine-specific corrinoid protein] + ammonia. |
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