mitomycin 6-O-methyltransferase EC#: 2.1.1.316; ChemWhat Code: 1376598
Product Name | mitomycin 6-O-methyltransferase |
Example Structure | |
Synonyms | MmcR |
EC Number | 2.1.1.316 |
CAS Registry Number | |
Comments | The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B. |
Cofactor | |
History | |
Reactions | (1) S-adenosyl-L-methionine + 6-demethylmitomycin A = S-adenosyl-L- homocysteine + mitomycin A. (2) S-adenosyl-L-methionine + 6-demethylmitomycin B = S-adenosyl-L- homocysteine + mitomycin B. |
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