molybdopterin synthase EC#: 2.8.1.12; ChemWhat Code: 1379069
| Product Name | molybdopterin synthase |
| Example Structure |  |
| Synonyms | CnxG, CnxH, MoaB, MoaD, MoaE, MoaX, MPT synthase, Rv3323c, TTHA0341 |
| EC Number | 2.8.1.12 |
| CAS Registry Number | |
| Comments | Catalyses the synthesis of molybdopterin from cyclic pyranopterin phosphate. Two sulfur atoms are transferred to cyclic pyranopterin phosphate in order to form the characteristic ene-dithiol group found in the molybdenum cofactor. Molybdopterin synthase consists of two large subunits forming a central dimer and two small subunits (molybdopterin-synthase sulfur-carrier proteins) that are thiocarboxylated at the C-terminus by EC?2.8.1.11, molybdopterin synthase sulfurtransferase. The reaction occurs in prokaryotes and eukaryotes. |
| Cofactor | |
| History | |
| Reactions | Cyclic pyranopterin phosphate + 2 [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + H(2)O = molybdopterin + 2 [molybdopterin- synthase sulfur-carrier protein]. |
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